Search on: CATHEPSIN K 
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Descriptor English:   Cathepsin K 
Descriptor Spanish:   Catepsina K 
Descriptor Portuguese:   Catepsina K 
Tree Number:   D08.811.277.656.224.405
D08.811.277.656.262.500.156
D08.811.277.656.300.200.156
Definition English:   A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme. 
Indexing Annotation English:   Cathepsin X, an obsolete multi-meaning term appearing in older literature goes here or at CATHEPSIN Z: check text; Cathepsin O and Cathepsin O2 in older literature go here.
History Note English:   2010(1984) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   53600 
Unique Identifier:   D056657 

Occurrence in VHL:
 

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